1. Ectopic Fat Disposition and Lipotoxicity.

Dietary fat and heart failure: moving from lipotoxicity to lipoprotection.

There is growing evidence suggesting that dietary fat intake affects the development and progression of heart failure. Studies in rodents show that in the absence of obesity, replacing refined carbohydrate with fat can attenuate or prevent ventricular expansion and contractile dysfunction in response to hypertension, infarction, or genetic cardiomyopathy. Relatively low intake of n-3 polyunsatu...

Leptin Resistance and Lipolysis of White Adipose Tissue: An Implication to Ectopic Fat Disposition and Its Consequences

Sleep apnea and ectopic fat deposition.

Indeed, as pointed out by the authors, OSA is linked to a multitude of derangements of metabolism, including diabetes mellitus, hyperlipidemia, and others. It is essential to understand whether OSA-targeted therapy will prevent or halt the development of associated cardiometabolic conditions. One potential way to do this is to detect populations at risk at early stages, when the impact of OSA t...

Adipose tissue inflammation and ectopic fat accumulation

Obesity may be viewed as a state of chronic, low-grade inflammation, which plays an important role in the development of the metabolic syndrome. Indeed, unbalanced production of proand anti-inflammatory adipocytokines seen in visceral fat obesity plays a critical role in the pathophysiology of the metabolic syndrome. Recent evidence has revealed that adipose tissue macrophages may participate i...

- 1 - Character , Attitude and Disposition

Recent debate over the empirical psychological presuppositions of virtue ethics has focused on reactive behavioural dispositions. But there are many character traits that cannot be understood properly in this way. Such traits are well described by attitude psychology. Moreover, the findings of attitude psychology support virtue ethics in three ways. First, they confirm the role of habituation i...